Another important center included in the municipality of Roseto is Cologna, of Roman origin, often mentioned in medieval documents above all in relation to the presence of the Monastery of San Salvatore in Bozzino.
The numerous archaeological findings show that the territory of current Roseto degli Abruzzi was already inhabited in the Roman Age. For centuries Montepagano was the main center in the area. It is mentioned in several documents both for the presence of the Emperor Lotharius and because it was part of the possessions of the Abbey of San Giovanni in Venere. Remains of the ancient medieval fortifications can still be identified in the four entrance doors and in the Romanesque-Baroque bell tower built in red bricks, belonging in the past to the now lost church of Sant'Antimo
In 1251 Montepagano was included in the newly established Diocesis of Atri. In 1424 the Acquaviva family obtained lordship over the territory of Montepagano, which they were to keep up to the French occupation in 1806 and consequent abolition of feudal rights.